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An evaluation of a SVA retrotransposon in the FUS promoter as a transcriptional regulator and its association to ALS.

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Genetic mutations of FUS have been linked to many diseases including Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Lobar Degeneration. A primate specific and polymorphic retrotransposon of the SINE-VNTR-Alu (SVA) family is present upstream of the FUS gene. Here we have demonstrated that this retrotransposon can act as a classical transcriptional regulatory domain in the conte... https://www.trangtinamthuc.com/product-category/sodas-beverages/
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