Numb was originally discovered as an intrinsic cell fate determinant in Drosophila by antagonizing Notch signaling. The present study is to characterize the role of Numb in oxidative stress-induced apoptosis of renal proximal tubular cells. Exposure of NRK52E cells to puromycin aminonucleoside (PA) resulted in caspase 3-dependent apoptosis. https://www.ngetikin.com/deal-time-Orange-Zinger-Tomato-Container-Cherry-Tomatoes-Lycopersicon-Esculentum-5-Seeds-mega-super/